Winner:
La Liga (8): 2004-05, 2005-06, 2008-09, 2009-10, 2010-11, 2012-13, 2014-15, 2015-16
Copa del Rey (5): 2008-09, 2011-12, 2014-15, 2015-16, 2016–17
UEFA Champions League (4): 2005-06, 2008-09, 2010-11, 2014-15
Supercopa de España (7): 2005, 2006, 2009, 2010, 2011, 2013, 2016
UEFA Super Cup (3): 2009, 2011, 2015
FIFA Club World Cup (3): 2009, 2011, 2015

Runner-up:
La Liga* (2): 2011-12, 2013-14
Copa del Rey (2): 2010-11, 2013-14
Supercopa de España (2): 2012, 2015
UEFA Super Cup: 2006

^{*Note: No official medal/honour is received for finishing second in La Liga.}

Winner:
Olympic Gold Medal: 2008
FIFA U-20 World Cup: 2005

Runner-up:
FIFA World Cup: 2014
Copa América: 2007, 2015, 2016

Barcelona:
La Liga All Time Top Scorer Honorary Golden Boot: 2015
FIFA Ballon d'Or (4): 2010, 2011, 2012, 2015
Ballon d'Or: 2009
FIFA World Player of the Year: 2009
World Soccer Player of the Year (3): 2009, 2011, 2012
World Soccer Greatest XI of All Time: 2013
Onze d'Or (3): 2009, 2011, 2012
European Golden Shoe (3): 2010, 2012, 2013
UEFA Best Player in Europe Award: 2010-11, 2014-15
UEFA Club Footballer of the Year: 2009
UEFA Goal of the Season: 2014-15
FIFA Club World Cup Golden Ball (2): 2009, 2011
UEFA Champions League Top Goalscorer (6): 2009, 2010, 2011, 2012, 2015, 2017
UEFA Champions League Forward of the Year: 2009
AS.com La Liga Player of the Year: 2014-15
Trofeo Alfredo Di Stéfano (4): 2008–09, 2009–10, 2010–11, 2014-15
Don Balón Award (3): 2007, 2009, 2010
L'Équipe Champion of Champions: 2011
LFP Best Player (5): 2009, 2010, 2011, 2012, 2013
LFP Best Forward (5): 2009, 2010, 2011, 2012, 2013
La Liga Ibero-American Player of the Year (5): 2007, 2009, 2010, 2011, 2012
FIFPro World Young Player of the Year (3): 2006, 2007, 2008
World Soccer Young Player of the Year (3): 2006, 2007, 2008
Bravo Award: 2007
Golden Boy: 2005
Marca Legend Award: 2009
ESPY Awards Best International Athlete (2): 2012, 2015
El País King of European Soccer (4): 2009, 2010, 2011, 2012
IFFHS World's Top Goal Scorer (2): 2011, 2012
IFFHS World's best Top Division Goal Scorer (2): 2012, 2013
FIFA/FIFPro World XI (10): 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014, 2015, 2016, 2017
UEFA Team of the Year (6): 2008, 2009, 2010, 2011, 2012, 2014, 2015
ESM Team of the Year (7): 2006, 2008, 2009, 2010, 2011, 2012, 2013
Copa del Rey Top Goalscorer (2): 2010–11, 2013–14
Argentine Sportsperson of the Year Award: 2011
Olimpia de Plata (8): 2005, 2007, 2008, 2009, 2010, 2011, 2012, 2013
Gazzetta dello Sport Sportsman of the Year: 2011

Argentina:
2014 FIFA World Cup: Golden Ball (Best player)
2014 FIFA World Cup: Dream Team
FIFA U-20 World Cup Player of the Tournament: 2005
FIFA U-20 World Cup Top Goalscorer: 2005
Copa América Young Player of the Tournament: 2007
Copa América Top Assist Provider: 2011, 2015
Copa América Best Player:
2015

World:
Most FIFA Ballon d'Or awards: 4
Guinness World Records title for the most goals in a year: 91 goals
Most consecutive European Cup top scorer awards: 4
Most Goals Scored in 1 UEFA Champions League Match (joint with Luiz Adriano): 2012
Most Hat-Tricks Scored in UEFA Champions League
Most Man of the Match Awards in a Single World Cup: 4 (2014)

Spain:
Most goals scored for a single club: 546 goals
Most goals scored in La Liga history: 378 goals
Most assists made in La Liga history: 113 assists
Most goals scored in La Liga in a season: 50 goals (2011-12)
Most consecutive La Liga matches scored in: 21 matches (33 goals)
Most La Liga hat-tricks in a season: 8 hat-tricks (shared with Cristiano Ronaldo)
Youngest player to score 200 La Liga goals: 25 years
First player to score at least 25 goals in five consecutive seasons in La Liga (shared with Cristiano Ronaldo): 2009–10 to 2013–14
First player to score at least 20 goals in six consecutive seasons in La Liga: 2008–09 to 2013–14
Most goals scored in El Clásico matches: 25 goals
Most hat-tricks in El Clásico matches: 2
Most goals scored in Derbi Barceloní: 12
Most goals scored in the Supercopa de España: 10 goals

Barcelona:
Most goals scored in El Clásico matches: 21 goals
Most goals scored in Derbi Barceloní: 12
Top scorer in official competitions: 397 goals
Top scorer in La Liga: 286 goals
Top scorer in UEFA Champions League: 77 goals
Top scorer in international competitions: 80 goals
Most hat-tricks in official competitions: 32 hat-tricks
Most hat-tricks in La Liga: 24 hat-tricks
Most away goals scored in Barcelona history in La Liga: 120 goals

Argentina:
Most goals scored in a year (national team): 12 goals (shared with Gabriel Batistuta)
Youngest Argentinian Player to have Scored in World Cup Finals:
18 years and 357 days